Beta-agonists: faamatalaga, gaoioiga lisi o fualaau faasaina

Taitasi o fualaau faasaina e faatatau i vaega pharmacological patino. O lona uiga o nisi o fualaau faasaina le faiga lava lea e tasi o gaoioiga, faailoga ma aafiaga itu. O se tasi o vaega tetele o vailaau - lenei o se agonists beta-adrenergic. O nei fualaau faasaina o loo lautele faaaogaina i le togafitiga o pathologies respiratory ma cardiovascular.

O le a I-agonists?

Beta-agonists - o se vaega o masini faafomai o loo faaaoga i le togafitia o faamai eseese. I le tino, latou noatia i receptors patino o loo i le maso lamolemole o le bronchi, tō, loto ma le aano o le tino vascular. O fegalegaleaiga mafua a faaosofia o le sela beta. O se taunuuga o le faatoaagaina mai o faiga physiological eseese. I le saisaitiaina o B-agonists e receptors uunaʻia le tuuina atu o pule moni, e pei o dopamine ma adrenaline. O le isi igoa mo nei tuufaatasi - beta-agonists. aafiaga Major ai - saoasaoa o le loto fua faatatau, faateleina toto ma faaleleia conductivity bronchial.

Beta-agonists: o gaoioiga i le tino

Beta-agonists ua vaevaeina i V1- ma agonists B2-adrenergic. Receptors mo nei mea ua i ai i le totoga o loo i totonu. I le noatia ai i latou beta-agonists taitai atu ai i le faatoaagaina mai o le tele o faiga i totonu o le tino. O loo i ai nei aafiaga o le B-agonists:

1. Faateleina automaticity ma le faaleleia conductivity fatu.
2. fua faatatau loto faateleina.
3. Saoasaoa o lipolysis. I le faaaogaina, B1-agonists foliga mai i le toto saoloto acids puta lea o le oloa o le faamalepeina o triglycerides.
4. toto faateleina. O lenei aafiaga ua mafua ona o le faaosofia o le renin-angiotensin-aldosterone faiga (RAAS).

I le suiga o loo lisiina i le tino e tau atu i le saisaitiaina o agonists receptors B1. o loo i ai i latou i le loto maso, o le toto ipu, adipose pepa solo ma le meafaigaluega juxtaglomerular o sela fatugao.

ua tu receptors B2 i le bronchi, tō, maso skeletal, neura tutotonu. I le gata i lea, oi latou o ni ipu o le loto ma le toto. Beta-2-agonists mafua ai le aafiaga lenei:

1. Improvement o conductivity bronchial. O lenei aafiaga ua tatau ona totogi atu i le malologa o maso lamolemole.
2. Saoasaoa o glycogenolysis i le musele. O se taunuuga o maso skeletal vave ma sili atu ona faaitiitia.
3. O le malologa o le myometrium.
4. Saoasaoa glycogenolysis i sela ate. O lenei e tau atu i le faateleina o tulaga suka toto.
5. fua faatatau loto faateleina.

O le a fualaau faasaina o se vaega o le B-agonists?

Fomai masani ona faatonuina beta-agonists. Fualaau faasaina i ai i lenei vaega pharmacological, vaevaeina i fualaau puupuu ma anapogi faia. I le faaopoopo atu, maotua fualaau faasaina na i ai se aafiaga filifili i totoga patino. O nisi o fualaau faasaina galulue saʻo i luga o le V1- ma V2-receptors. O le vailaau iloa-e sili ona lelei mai le vaega o beta-agonists o fualaau faasaina "Salbutamol", "fenoterol", "Dopamine". O le agonists faaaogaina i le togafitia o faamai chronic ma fatu. Foi o nisi oi latou o loo faaaogaina i totonu o tuutuuga o le tigaina (fualaau faasaina "Dobutamine"). Itiiti masani fualaau faasaina i totonu o lenei vaega o loo faaaogaina i faiga gynecological.

Faavasegaina o beta-agonists: ituaiga o vailaau

Beta-agonists - lenei vaega pharmacological, lea e aofia ai se vaega tele o fualaau. Mea lea, ua vaevaeina i latou i ni vaega. Faavasegaina B-agonists e aofia ai:

1. beta-adrenergic lē filifili agonists. O lenei vaega e aofia ai fualaau faasaina "ortsiprenalina" ma le "Isoprenaline".
2. Filifili B1-agonists. o loo faaaogaina i latou i le uarota cardiology ma tigaina. O sui o lenei vaega o fualaau faasaina o le "Dobutamine" ma le "Dopamine".
3. beta-2-agonists filifili. O lenei vaega e aofia ai fualaau faaaogaina mo faamai o le faiga respiratory. O lea, o le agonist filifili B2 vaevaeina i fualaau faasaina puupuu-galue, ma fualaau faasaina i ai se aafiaga tumau umi. O le vaega muamua e aofia ai fualaau "fenoterol", "terbutaline" "Salbutamol" ma le "hexoprenaline". Long-le faia i fualaau faasaina - o se fualaau faasaina "Formoterol", "Salmeterol" ma le "indacaterol."

Faailoga I-agonists

Faailoga mo le faaaogaina o le B-agonists e faalagolago i le ituaiga o fualaau faasaina. Beta-agonists o gaoioiga lē filifili Ua faaaoga nei le faigata. Na muamua atu, sa faaaogaina e faia ai nisi ituaiga o arrhythmias, worsening conduction fatu, sela bronchial. O lenei fiafia e fomai e faatonuina filifili B-agonists. Lo latou lelei o ia i latou mamao aafiaga itiiti itu. I le faaopoopo atu, fualaau faasaina filifili faigofie ona faaaoga, e pei na aafia ai totoga patino.

Faailoga mo B1-agonists faamoemoe:

1. toilalo loto matuitui.
2. O le teʻi o so o se etiology.
3. Pau.
4. Decompensated faaletonu loto.
5. Seasea - faamaʻi loto ischemic tulaga matuia.

B2-agonists faafoeina i sela bronchial, maʻi faaumiumi faalavelave chronic. I le tele o tulaga, o nei fualaau faasaina o loo faaaogaina i le tulaga o aerosols. O nisi taimi medikament "fenoterol" o loo faaaogaina i gynecological faiga e faifai galue ai, ma le puipuia o fafano lona maitaga. I lenei tulaga, o lo o faafoeina intravenously le fualaau faasaina.

I nisi o tulaga, e contraindicated B-agonists?

E tatau ona manatua o fualaau faasaina vaega A beta-agonists maua se numera o contraindications ma aafiaga itu. E moni lava lenei i le agonists lē filifili. Itu aafiaga o nei fualaau faasaina - .. O le atinae o hyperglycemia, tremors itutino, loto faaletonu pao, excitation neura autu, ma isi Beta-1 agonists o fualaau faasaina malosi, o lea o loo faaaogaina na i tulaga o manaoga faavavave. ua contraindicated i latou i le gasegase ma se talafaasolopito o sea pathology: arrhythmia ventricular, stenosis subaortic, pheochromocytoma. Foi, e le mafai ona faaaogaina ma le tamponade fatu.

B2-agonists ua contraindicated i le mataupu nei:

1. Le faapalepale e beta-agonists.
2. Maitaga faigata i le toto, abruption placental, lamatia fafano lona maitaga.
3. Fanau i lalo o le 2 tausaga.
4. faagasologa Inflammatory i myocardium, arrhythmias fatu.
5. Diabetes mellitus.
6. stenosis Aortic.
7. Toto maualuga.
8. toilalo loto matuitui.
9. Thyrotoxicosis.

Medicament "Salbutamol": faatonuga mo le faaaogaina

Fualaau faasaina "Salbutamol" e faatatau i B2-agonists o le faatinoga puupuu. E faaaogaina i le syndrome o faalavelaveina bronchial. E masani ona faaaoga i aerosols mo 1-2 inumaga (0.1-0.2 mg). Fanau sili o le faia o le manavaina i totonu e ala i a nebulizer. O loo i ai se faiga laupapa foi o le fualaau faasaina. O le inumaga mo tagata matutua o 6-16 mg i le aso.

"Salbutamol": tau fualaau faasaina

O le fualaau oona faaaogaina o monotherapy i sela agamalu. Afai o le onosai ei ai tulaga feololo po o le ogaoga o le faamaʻi, fualaau faasaina faaaogaina faaumiumi (umi-galue beta-agonists). O i latou o le togafitiga faavae o sela bronchial. le faaaogaina o fualaau faasaina "Salbutamol" mo se fesoasoani vave o le osofaiga o le manava. O le tau o le fualaau faasaina e mai le 50 i le 160 rubles e faalagolago i le gaosia ma le inumaga o lo o aofia i totonu o le ipu.